5.0 REFERENCES.
Acebey-Castellon,L.,Voutquenne-Nazabadioko,L.,Doan,H.,Roseau,N.,Bouthagane,N., Muhammad, D., &Lavaud, C. (2011). Triterpenoid saponins fromSymplocos lancifolia. Journal of Natural Products, 74(2), 163–168.
Aiyegoro,A.,& Okoh,L.(2009).Useofbioactiveplantproductsincombinationwith standard antibiotics:Implicationsinantimicrobialchemotherapy. Journalof Medicinal Plants Research, 3(13),1147–1152.
Aksel,B.(2010).Bioactivecompoundsinplants:benefitsandrisksformanandanimals.
Oslo, Norway: TheNorwegian Academyof Science andLetters. 7-30.
Alan, T., Jeffrey, D., Matthew, S., Marlene, O., Michael, R., & Brian, C. (2005).I-DIRT, A GeneralMethodforDistinguishing betweenSpecificandNonspecificProtein Interactions.Journal of Proteome Research,4 (1),1752-1756.
Alanis,J.(2005).Resistancetoantibiotics:areweinthepost-antibioticera?Archivesof
Medical Research, 36(6), 697–705.
Alekshun,N., &Levy,B.(2007). Molecularmechanismsof antibacterialmultidrug resistance. Cell, 128(6),1037–50
Alqahtani,A.,Tongkao-On,W.,Li,M.,Razmovski,V.,Chan,K.,&Li,Q.(2015).Seasonal VariationofTriterpenesandPhenolicCompoundsinAustralianCentella asiatica(L.) Urb. Phytochemical Analysis, 26(6), 436–443.
Altıok,E.,Bayçın,D.,Bayraktar, O.&Ulku S.(2008).Isolationof Polyphenolsfromthe ExtractsofOliveLeaves(OleaeuropaeaL.) by AdsorptiononSilk Fibroin.Separation and Purification Technology,62 (2): 342-48.
Smith,A.(2013).Isolationtechniqueof bioactive moleculesfromplantandtheir Application.International Journalof CurrentTropicalMedicineandHealthResearch,1 (1), 1-4.
Andarwulan,N.,Batari,R.,Sandrasari,A.,Bolling,B.,&Wijaya,H.(2010).Flavonoid contentandantioxidantactivity ofvegetablesfromIndonesia.FoodChemistry,121(4),
1231–1235.
Andreas,O.,Dorte,B.,&Frank,Sc.(2014).Quantitativeproteomicsinthefieldof microbiology. Proteomics.14 (5), 547–565.
Anjana,D.,Acqua,D.,Jha,P.K.,&Innocenti,G.(2010).Variationintheactiveconstituent contents in Centella Asiaticagrown in different habitats in Nepal, 43–47.
Anton,Y.(2008).IntroductiontoPathwayAnalysis.In:SeanEkinsPathwayAnalysisfor
DrugDiscovery. New Jersey: John Wiley&Sons,Inc.,1-27.
Ariharan,V.,Devi,M.,&PrasadP.(2013).AntibacterialactivityofSauropusandRogynous
leaf extracts againstsomepathogenic bacteria. Rasayan J. Chem., 6 (2), 134-137.
Arthur, C. (2011). Morinda citrifolia L. (Noni, Cheese fruit). Available: http://www.flickr.com/photos/arthur_chapman/5763092741/in/photostream/Lastaccessed, 17/08/2015.
Arumugam,T.,Ayyanar,M., Pillai,K.,&Sekar,T.(2011). Phytochemicalscreeningand antibacterialactivity ofleafandcallusextractsofCentellaAsiatica.BangladeshJournal of Pharmacology, 6(1),55–60.
Asgari,S.,Shariati,P.,&Ebrahim-Habibi,A.(2013).Targetingacetatekinase:Inhibitorsas potential bacteriostatic. Journal of Micro. and Biotech., 23(11),1544–1553.
Asolkar,V.,etal.(2005).Glossary ofIndianMedicinalPlantswithactiveprinciple,Part1
NationalInstituteof Sci., Comm. andInformation Resources, CSIR,New Delhi.
Au,E.,Bell,W., Gilchrist,A.,Hiding, J.,Nilsson,T.,&Bergeron,J.(2007).Organellar proteomics to create thecellmap. Current Opinion in CellBiology, 19(4),376–85.
Azania,N.(2015).AReviewontheExtractionMethodsUses in MedicinalPlants, Principle, Strength, andLimitation. Med Aromat Plants, 4, 196.
Bakheet,M., &Doig, J. (2010). Properties and identification ofhuman protein drugtargets.
Bioinformatics, 25 (4), 451–457.
Balangcod,D.,Vallejo,L.,PatacsilM.,Apostol,O.,Laruan,M.,ManuelJ.,Cortez, S.,& Gutierrez,M.(2012).Phytochemicalscreeningandantibacterialactivity ofselected medicinalplantsofBayabas,Sablan,BenguetProvince,Cordillera Administrative Region,Luzon.Indian Journal of traditional knowledge, 11 (4), 580-585.
Bandow,E.,Brotz,H.,Ole,I.,Labischinski,H.,Hecker,M., Bro,H.,&Leichert,O.(2003).
ProteomicApproachtoUnderstandingAntibioticAction.AntimicrobialAgentsand
Chemotherapy, 47(3), 948-955.
Bantscheff,M.,Schirle,M.,Sweetman,G.,Rick,J.,&Kuster,B.(2007).Quantitativemass spectrometryinproteomics:Acriticalreview.AnalyticalandBioanalyticalChemistry,
389 (4), 1017–1031.
BarretoL.,CarvalhoE.,MarcilioF.,ClebioF.,&HaroudoX.(2007).The molluscicidalactivity ofthe extracts and aucubin from Vitexgardneriana (Verbenaceae) on embryos of Biomphalaria glabrata.Latin American Journalof Pharmacy,26(3), 339-343.
Bart,H.(2011).ExtractionofNaturalProductsfromPlants–AnIntroduction.Editedby
Hans-JorgBartand Stephan Pilz, 1-26.
Batra,P.,&Sharma,K.(2013).Anticancerpotentialofflavonoids:recenttrendsandfuture perspectives. 3Biotech,3(6), 439-459.
Bauer,W.,Kirby,M.,Sherris,C.& Turck,M.(1966).Antibioticsusceptibilitytesting bya standardized single diskmethod. Amer.I. Clin. Pathol. 45, 493-6.
Becher,D., Hempel,K.,Sievers, S.,Zuhlke,D.,Pane-Farre,J.,Otto,A.,etal.(2009).A proteomicviewofanimportanthumanpathogen–towardsquantifying theentire Staphylococcus aureus proteome. PLoSOne, 4, 8176.
Belenky,P.,&Collins,J.(2011).AntioxidantStrategiestoTolerateAntibiotics.Science,
334 (6058), 915–916.
Bent,S.,Richard,K.(2004).CommonlyusedherbalmedicinesintheUnitedStates:areview
TheAmerican Journal of Medicine, 116, 478-485
Berka-Zougali, B., Ferhat, M. A., Hassani, A., Chemat, F., &Allaf, S. (2012). Comparative study ofessentialoilsextractedfromAlgerianMyrtuscommunisL.leavesusing microwavesandhydrodistillation.InternationalJournalofMolecularSciences,13(4),
4673–4695.
Bernal,J.,Mendiola, A.,Ibanez,E.,&Cifuentes,A.(2011).Advancedanalysisof nutraceuticals. Journal of Pharmaceutical andBiomedical Analysis, 55(4),758-774.
Bhakta,D., Sivaramakrishna,A.,&Siva,R.(2013).Bioactiveiridoidglycosideisolated fromMorindatinctoria(Roxb.) rootsexhibittherapeutic efficacy.IndustrialCropsand Products, 42(1), 349–356.
Bharti,K.,&Roy,R.(2012).Quantitative1HNMRspectroscopy.Trac -Trendsin
Analytical Chemistry, 35, 5–26.
Bio-Rad. (2014). 2-D Electrophoresis Workflow Howto Guide. Available:http://www.bio- rad.com/webroot/web/pdf/lsr/literature/Bulletin_2651.pdf.Last accessed 08/09/2014.
Bobzin,C.,Yang, S.,&Kasten, P.(2000). Applicationof liquidchromatography-nuclear magneticresonancespectroscopy toidentifying naturalproducts.Journalof chromatography.B,Biomedical sciences and applications, 748(1), 259–67.
Bonar,E.,Wojcik,I.,&Wladyka,B.(2015).ProteomicsinstudiesofStaphylococcusaureus
virulence. ActaBiochemical Polonica, 62(3), 367–381.
Bradley,S.(2014).Whichantibioticis forresistantGram-positives,andwhy?TheJournalof
Infection, 68 (1), 63–75.
Bradshaw, R.,&Burlingame,A.(2005).From Proteinsto Proteomics.InternationalUnion of Biochemistryand MolecularBiologyLife, 57(4-5), 267–272.
Breu,F.,GuggenbichlerS.,&Wollmann,(2008).AntimicrobialResistanceinDeveloping
Countries. SpringerNewYork Dordrecht HeidelbergLondon, 3-15.
Bronner, E.&Beecher,R.(1995). Extractionandmeasurementof prominentflavonoidsin orange andgrapefruitjuice concentrates. J. Chro.,705 (2), 247-256.
Brotz-Oesterhelt,H.,&Brunner,A.(2008).Howmanymodesofactionshouldanantibiotic have?Current Opinion inPharmacology, 8(5), 564–573.
Brotz-Oesterhelt,H.,Bandow,E.,&Labischinski,H.(2005). Bacterialproteomicsandits rolein antibacterial drug discovery. Mass SpectrometryReviews, 24(4), 549–65.
BucarF., WubeA.&SchmidM.(2013).Naturalproductisolation–how togetfrom biological material to pure compounds. Natural product reports, 30, 525-545.
Bueno, J.(2012).InVitroAntimicrobialActivity ofNaturalProductsUsing Minimum Inhibitory Concentrations:LookingforNewChemicalEntitiesorPredictingClinical Response. Medicinal& Aromatic Plants, 1(07),1-2.
Burbaum, J., & Tobal, M. (2002).Proteomics in drugdiscovery.Current Opinion in
Chemical Biology, 6(4),427-33.
Burchmore, R. (2014). Mappingpathways to drugresistancewith proteomics. Expert
Reviewof Proteomics, 11(1), 1-3.
Burge,S.,Kelly,E.,Lonsdale, D., Mutowo-Muellenet, P.,McAnulla,C.,Mitchell,A.,& Hunter, S.(2012). ManualGOannotationof predictive proteinsignatures:TheInterPro approachtoGOcuration.Database:The Journalof BiologicalDatabasesandCuration, (2), 1-6.
Bush,K., &Pucci, J. (2011). Newantimicrobial agents on thehorizon. Biochemical
Pharmacology, 82(11), 1528–1539.
CalixtoB.,SantosA.,Cechinel,V.,& Yunes, A.(1998).AReviewofthe Plantsofthe GenusPhyllanthus:TheirChemistry, Pharmacology,andTherapeutic Potential. The medicinal research review, 18 (4), 255.
Cappadona,S.,Baker,R.,Cutillas,R.,Heck,R.,&Breukelen,B.(2012).Currentchallenges insoftwaresolutionsformassspectrometry-basedquantitativeproteomics.AminoAcids,
43 (3), 1087–1108.
Carlos,F.,&Cuevas,A.(2010). Global Perspectivesof Antibiotic Resistance.In: Antimicrobial Resistancein DevelopingCountries, Springer, 3-15.
Cash,P.(2003)Proteomicsofbacterialpathogens.AdvancesinBiochemicalEngineering,
83, 93-115.
Chanda,S.,VyasB.,Vaghasiya,Y.,&Patel,H. (2010).Globalresistancetrendsandthe potentialimpactofmethicillin-resistantStaphylococcusaureus(MRSA)anditssolutions. In:CurrentResearch, Technology, andEducation.Microbiology BookSeries,Formatx, Badazoj, Spain,529-536.
Chandra,P., Mathur,S.,&Sharma, A.(2014).Antimicrobialscreening ofCaesalpinia pulcherrima(L.)SW.againstpathogenicmicroorganism. Souvenirof4thInternational ScienceCongress,4(1),243.
Chang, M.(1998).Liver-protectiveactivities ofaucubin derived from traditional oriental medicine. Res Common Mol Pathol Pharmacol, 102, 189-204.
Charles,B.,&Spainhour, A.(2005).NaturalProducts.In:ShayneCoxGad.DrugDiscovery
Handbook. New Jersey: John Wiley&Sons,Inc.,11-72.
Charles,W.,Gehrke S.,Robert,L.,WixomM., & Ernst,B.(2001).Thebeginningsof chromatography-Thepioneers(1900–1960).In:C.W.Gehrke,R.L.WixomandE.Bayer chromatographyacenturyofdiscovery1900–2000,thebridgetothesciences/technology. Amsterdam, theNetherland: ElsevierscienceB.V., 1-38.
Chauhan,A.,Mittu,B.,& Chauhan,P.(2013).International JournalofFundamental& Applied Sciences NosocomialInfections: A BriefReview, 2(3), 50–55.
Chen,P.,&Du,H.(2007).Targetvalidation:Adoortodrugdiscovery.DrugDiscoveries
&Therapeutics, 1(1), 23–9.
Choi, J.,Tai,H.,Cuong,M.,Kim,H.,&Jang,D.(2012).Antioxidativeandanti-inflammatory effectof quercetinanditsglycosidesisolatedfromimpact(Cratoxylum formosum). Food Science and Biotechnology, 21(2), 587–595.
Clatworthy,E.,Pierson,E.&Hung,T.(2007).Targeting virulence:anewparadigmfor antimicrobial therapy. Nat Chem Biol, 3, 541-548.
Claudia,A.,Stefanie,K.,Holger,B.,&Michael,B.(2012).Nativepolyacrylamidegels.
Methods Mol Biol., 869,49â€53.
Clinical and Laboratory Standards Institute. (2007). Performance Standards for
AntimicrobialSusceptibilityTesting:SeventeenthInformationalSupplement.940West
ValleyRoad, Suite1400, Pennsylvania,USA. Wayne, P. A.
Coates,A.,& Hu,Y.(2007).Novelapproachestodeveloping newantibioticsforbacterial infections. British Journal of Pharmacology, 15, 1147–1154.
College, G.,&Naka, K.(2009). Antimicrobial and Antifungal ActivityofCentella asiatica
(L.) Urban, Umbeliferae,2(2), 328–330.
Collins, J., Rudkin,J., Recker,M.,Pozzi,C.,O’Gara,P.,& Massey,C.(2010).Offsetting virulence andantibiotic resistance costsbyMRSA.4, 577-584.
Cooper,R.,&Carucci, J.(2004).Proteomicapproachestostudyingdrugtargetsand resistancein plasmodium. Current DrugTargets.Infectious Disorders, 4(1), 41–51.
Cordwell,J.,Larsen,R.,Cole,T.,& WalkJ.(2002)Comparative proteomicsof Staphylococcusaureusandtheresponseofmethicillin-resistantandmethicillin-sensitive strains to Triton X-100. Microbiology, 148, 2765-2781.
Cowan,M.(1999).Plantproductsasmicrobialagents.ClinicalMicro.Rev.,12(4),564-582. Cragg,G.,&Newman,J.(2005).Drugdiscoveryanddevelopmentfromnaturalproducts:
Thewayforward. Proceedings of the11th NaturalProduct, 1(5), 56–69.
Cragg,M.,&Newman,J.(2014).Naturalproducts:acontinuingsourceofnoveldrugleads.
NIH Public Access, 1830(6), 3670-3695.
Cseke, J., Kirakosyan,A., Kaufman,B., Warber,L., Duke,A., &Brielmann,L.(Eds.). (2006). Natural productsfrom plants (2nd Ed.).BocaRaton:Taylor&Francis.
Csermely,P.,Korcsmaros,T.,Kiss, M.,London,G.,& Nussinov,R.(2013). Structureand dynamicsofmolecular networks:anovelparadigmofdrug discovery:acomprehensive review. Pharmacology& Therapeutics, 138(3), 333–408.
Dalgaard, P.,&Koutsoumanis,K.(2001).Comparisonofmaximumspecificgrowthrates andlagtimesestimatedfromabsorbanceandviablecountdatabydifferentmathematical models. Journal of Microbiological Methods, 43(3), 183–196.
Daniel,L.(2002).IntroductiontoProteomicsToolsfortheNewBiology.Totowa,New
Jersey: HumanaPressInc., 1-25.
Das,K. (2010). Techniquesforevaluating medicinalplantproductsasantimicrobial agents:Current methods and futuretrends of Medicinal Plants, 4(2), 104–111.
Dash,K.,Faruquee,M.,Biswas,K.,Alam,K.,Sisir,M.,&Prodhan,K.(2011).Antibacterial andAntifungalActivitiesofSeveralExtractsofCentellaAsiaticaL.againstSomeHuman Pathogenic Microbes,LifeSci. and Med., 1–5.
Da-Silva,F.,De-Oliveira,G.,Mendes,I.,Da-Costa,T.,Donizeti,S.,& De-Oliveira,T. (2014). Evaluationof acute toxicity,antibacterialactivity,andmode of actionof the hydroethanolicExtractofPiperumbellatumL.JournalofEthnopharmacology,151(1),
137–143.
David, H.(2015). Methicillin-Resistant Staphylococcus aureus (MRSA)Skin and Soft
Tissue Infections.Available: http://www.hivwebstudy.org/cases.Last accessed May
2015. Universityof Washington School of Medicine.
David,J.(2000).Proteinstructurepredictioninthepostgenomicera.CurrentOpinionin
Structural Biology,10 (1), 371–379.
Davies, J., &Davies, D. (2010). Originsand Evolution of Antibiotic Resistance.
Microbiologyand MolecularBiologyReviews, 74(3), 417–433.
Da-WeiH., Sherman,T. &Lempicki,A.(2009).Bioinformatics enrichmenttools:paths toward thecomprehensive functionalanalysisof largegenelists. Nucleic acids research,
37, 1-13.
Debnath,S.,Dinda, B.,Banik,R.,Noriko,S.,Yoshihiro,H.(2011). Iridoid glucosides from
Wendland tinctoriaroots. Nat. Prod. Commun.,6, 747–748.
DengS., Palu, K., West, J., Su,X., Zhou, N.,&Jensen, C. (2007).LipoxygenaseInhibitory
ConstituentsoftheFruitsofNoni(MorindacitrifoliaL.)CollectedinTahiti.JNatProd.,
70 (5), 859-862.
Deng, S., West, J.,Jensen,J., Basar, S., &Westendorf,J. (2009). Development and validationofanRP-HPLCmethodfor theanalysisofanthraquinonesinnonifruitsand leaves. Food Chemistry,116(2), 505–508.
Deurenberg,H.&Stobberingh,E.(2008).TheevolutionofStaphylococcusaureus.Infect
Genet Evol 8, 747-763.
Devkota,A.,Dall,S.,Comai,S.,Innocenti,G.&Jha,K.(2010).CentellaAsiatica(L.)Urban fromNepal:quantitativeanalysisof samplesfromseveralsites,andselectionof high terpenecontainingpopulations for cultivation. Bioch. Sys. and Eco., 38, 12–22.
Dias,D.,Urban,S.,&Roessner,U.(2012).AHistoricalOverviewofNaturalProductsin
DrugDiscovery. Metabolites, 2(2), 303–336.
Di-Luca,A.,Henry,M.,Meleady,P.,& O’Connor,R.(2015).Label-freeLC-MSanalysis of HER2+ breastcancercellline responsetoHER2inhibitortreatment.Daru.Journalof Facultyof Pharmacy, Tehran Universityof Medical Sciences, 23(1), 40.
Dimitri,S.,&Eric, B. (2009). GenomicsinDrugDiscoveryand Development.NewJersey: JohnWiley&Sons,Inc., 1-449.
Dinda,B., Debnath,S.,Harigaya,Y.(2007).Naturallyoccurring iridoids.Areview,part1.
Chem. Pharm. Bull,55, 159–222.
Djoukeng, J., Abou-Mansour, E., Tabacchi, R.,Tapondjou,A.,Bouda,H., &Lontsi, D. (2005).AntibacterialtriterpenesfromSyzygiumguineense(Myrtaceae).Ethnopharmacol,
101, 283-6.
Dolan,W.(2000). Starting outright,PartI -Selecting thetools.LCGC-Mag.Sep.Sci.13 (1), 12-15.
Dominique,F.(2014).PracticalaspectsofNMRsignalassignmentinlargerandchallenging proteins. ProgNucl Magn Reson Spectrosc., 0, 47–75.
Droit,A.,Poirier,G.,&Hunter,M.(2005).Experimentalandbioinformaticsapproachesfor interrogating protein-proteininteractionstodetermineproteinfunction. Journalof MolecularEndocrinology,34(2), 263–280.
Du,Q.,Jerz,G.,Chen,P.,&Winterhalter, P.(2001).Preparationoftriterpenoidsfrom CentellaAsiaticausinghighspeedcounter-currentchromatography withstep–gradient elution. Journal ofLiquid Chromatographyand Related Technology, 27, 2004-2007.
Duduku,K.,Rajesh,N., & Rosalam,S.(2012).PhytochemicalConstituentsandActivities ofMorindacitrifoliaL.In:VenketeshwerRao Phytochemicals-AGlobalPerspectiveof Their Rolein Nutrition and Health.InTech, 127-150.
Dunn,E.,Blaser,J.&Snyder,E.(1987).Two-dimensionalgelelectrophoresisand immunoblottingofCampylobacteroutermembraneproteins.InfectionandImmunity,55,
1564-72.
Dzidic,S.,Suskovic,J., &Kos,B.(2008).AntibioticResistanceMechanismsinBacteria: Biochemical and GeneticAspects. Food Tech.andBiotech. 46(1), 11–21.
Eisenberg,D.,Marcotte, E.M.,Xenarios, I.,Yeates,O.(2000).Proteinfunctioninthepost- genomicera.Nature. 405, 823-826.
Ejele,E.,Akalezi,I.,Iwu,C.,Ukiwe,N.,Enenebaku,K.,&Ngwu,U.(2014).Bioassay- GuidedIsolation, PurificationandCharacterisationof AntimicrobialCompoundfrom AcidicMetaboliteofPiperumbellatumSeedExtract.InternationalJournalofChemistry,
6 (1), 61–70.
Elangovan, N. (2013). Proteomics: Techniques, Applications, andChallenges.In: Debmalya,B.,Vasudeo,Z.,& VascoA.,OMICS:ApplicationsinBiomedical, Agricultural, and Environmental Sciences. US:CRC Press Taylor&Francis Group,3-43.
Elizabeth,B.& Murugesan,K.(2012).EvaluationofAntioxidantPotentialofMorinda citrifoliaL. Root Extract.Int. Res. J. of Pharmaceuticals,2 (4), 106-111.
Elliott, A., Weatherly,L.,Hawkins, S., Cranny,G., Chambers, D., Myers,L., Eastwood, A.,
&Sculpher, J.(2010).AneconomicmodelforthepreventionofMRSAinfectionsafter surgery:non-glycopeptide orglycopeptideantibioticprophylaxis.The EuropeanJournal of Health Economics,11,57-66.
Elliott,H.,Smith,S.,Parker,C.,&Borchers,C.(2010).Currenttrendsinquantitative
proteomics. JMass Spectrum,44 (12),1637â€60.
Eloff,J.(1998).WhichExtractantShouldBeUsedfortheScreeningandIsolationof
Antimicrobial Components from Plants?Journalof Ethnopharmacology,60, 1-8.
Entenza,J.M.,Betrisey,B.,Manuel,O.,Giddey,M.,Sakwinska,O.,Laurent,F.,&Bizzinib, A. (2014).Rapiddetection ofstaphylococcusaureusstrainswithreducedsusceptibility tovancomycinbyisothermalmicrocalorimetry.JournalofClinicalMicrobiology,52(1),
180–186.
Eymann,C.,Dreisbach,A.,Albrecht,D.,Bemhardt,J.,Becher, D.,Gentner, S.,Thi-Tam, L.,Bijttner, et al.(2004). Proteomics, 4, 2849-2876.
Fajardo,A.& Martinez,L.,(2008).Antibioticsassignalsthattriggerspecificbacterial responses. CurrOpin Microbiol., 11, 161-167.
Feist,P.,& Hummon,B.(2015).Proteomicchallenges:Samplepreparationtechniquesfor Microgram-Quantity proteinanalysisfrombiologicalsamples.InternationalJournalof MolecularSciences, 16 (2), 3537–3563.
Felmingham,D.,&Brown, D.(2001).Instrumentationinantimicrobialsusceptibility testing. Journal of Antimicrobial Chemotherapy, 48 (1), 81-85.
Feng,L., Jia,B., Jiang, J.,Zhu,M.,Chen,Y.,Tan,B.,&Shi,F.(2011).Combinationof activecomponents enhancestheefficacyofPrunellainthe preventionandtreatmentoflung cancer. Molecules, 15(11),7893-906.
Feteisi,H.,Achour,B.,Barber,J.,& Rostami-Hodjegan,A.(2015).Choice ofLC-MS MethodsfortheAbsoluteQuantificationofDrug-Metabolizing Enzymesand TransportersinHumanTissue:A ComparativeCostAnalysis. TheAAPSJournal,17 (12), 438–446.
Filomena,N.,Florinda,F.,Laura-De,M.,Raffaele,C.,&Vincenzo,F.(2013).Effectof
Essential Oils on Pathogenic Bacteria. Pharmaceuticals,6 (1), 1451-1474.
Fischer,A.,Yang,J.,Bayer,S.,Vaezzadeh,R.,Herzig,S.,Stenz,L.,&Fran,P.(2011).
Daptomycinresistancemechanismsinclinically derivedstaphylococcusaureusstrains assessed by acombinedtranscriptomicsandproteomicsapproach.Journalof Antimicrobial Chemotherapy, 66(8), 1696-1711.
Fleer,H.,&Verspohl,J.(2007).Antispasmodicactivityofanextractfrom Plantago lanceolataL.and someisolated compounds. Phytomedicine 14, 409-415.
Fleischmann, D.,Adams, D., White, O., Clayton, A., Kirkness,F., Kerlavage, R.,etal. (1995).Whole-genomerandomsequencingandassemblyofHaemophilusinfluenzaeRd. Science269, 496–512.
Fluit,C.,Visser,R.,&Schmitz,J.(2001).Moleculardetectionofantimicrobialresistance.
Clin MicrobiolRev 14, 836-871.
Fox,L. (2006). Thebusiness of developingantibacterials. Nat.Biotechnol.,24, 1521-1528. Freiberg,C.,Brötz-Oesterhelt,H.,&Labischinski,H.(2004).Theimpactoftranscriptome
and proteome analyses on antibiotic drugdiscovery. Current Opinion in Microbiology, 7 (5), 451–9.
Friesen,B.,McAlpine,B.,Chen,N.,&Pauli,F.(2015).CountercurrentSeparationof
Natural Products:An Update. Journal of NaturalProducts, 78(7), 1765–1796.
Galloway,D.,Bender, A.,Welch,M.,& Spring,R.(2009).Thediscovery ofantibacterial agentsusingdiversity-oriented synthesis.ChemicalCommunications (Cambridge, England), 18, 2446–62.
Gamez-Pozo, A., Berges-Soria, J., Arevalillo,M.,Nanni, P.,Lopez-Vacas,R., Navarro, H., Grossmann,J.,etal.(2015). CombinedLabel-Free Quantitative Proteomicsandmicro RNAExpressionAnalysisofBreastCancerUnravelMolecularDifferenceswithClinical Implications. Cancer Res. 75, 2243-2253.
Garo,E,Eldridge,R.,Goering,G.,DeLancey,E.,Hamilton,A.,Costerton,W.,&James,A. (2007).Asiatic acid and corosolicacid enhancethesusceptibilityof Pseudomonas aeruginosa biofilms to tobramycin. Antimicrob Agents Chemother, 51, 1813–1817.
Gayathramma,K.,Pavani,V.,& Raji,R.(2012).Chemicalconstituentsandantimicrobial activitiesofcertainplantspartsofSauropusandrogynusL. InternationalJournalof Pharma andBio Sciences, 3 (2), 561-566.
Gilar,M.,Jaworski,A.,&McDonald,S.(2014).Solventselectivityandstrengthinreversed- phaseliquidchromatographyseparationofpeptides.JournalofChromatography,1337,
140–146.
Gillet,L.C.,Navarro,P.,Tate,S.,Rost,H.,Selevsek,N.,Reiter,L.,&Aebersold,R.(2012).
Targeted Data Extraction of the MS/MS Spectra Generated by Data-independent
Acquisition:ANewConceptforConsistentandAccurateProteomeAnalysis.Molecular
&CellularProteomics, 11(6), 016717.
Gilmore,M.,&Washburn,P.(2010).Advances inshotgunproteomicsandtheanalysisof membraneproteomes. Journal of Proteomics, 73(11), 2078–2091.
Gordon, J., &Lowy, D.(2008).Pathogenesis ofMethicillin-Resistant Staphylococcus aureusInfection. ClinInfect Dis., 46 (5), 350–359.
Gordon,M.,&David,N.(2005).Plantsasasourceofanticanceragents.Journalof
Ethnopharmacology, 100(1-2), 72-79.
Gothandam,M.,Aishwarya,R.,&Karthikeyan,S.(2010).Preliminary screeningof antimicrobial propertiesof few medicinal plants,Journal of Phytology, 2(4), 1–6.
Goulet,H.,Daneluzzi, V.,Dupont,C.,Heym,B.,Page,B.,Almedia,K.,Auvert,B., Elkharrat,D.,&Rouveix,E.(2009).Aprospectivestudy ofantibioticprescribinginan emergencycareunit, Medicine ET maladies infectieuses, 39, 48-54.
Govindan,G., Sambandan,G.,Govindan,M.,Sinskey,A.,Vanessendelft,J.,& Adenan,I. (2007).Abioactive polyacetylene compoundisolatedfromCentellaAsiatica. Planta Medica, 73 (6), 597–599.
Graves,R.,&Haystead,J.(2002).MolecularBiologist’sGuidetoProteomics.Microbiology and MolecularBiologyReviews, 66(1), 39–63.
Gronow,M.,& Griffith,G.(1971).Rapidisolationandseparationofnon-histoneproteins of rat livernuclei. FEBSLett, 15,340–4.
Guerrera, C., & Kleiner,O.(2005).Application ofmass spectrometryin proteomics.
BioscienceReports, 25(1-2), 71–93.
Guido,F.,Pauli,U., Jaki,C.,Lankin,A.,&Ian,B.(2008). QuantitativeNMRofBioactive Natural Products. In: Steven M. Colegate, Russell J. Molyneux Bioactive Natural Products,Detection,Isolation,and StructuralDetermination.2nded.U.S.:Taylor &Francis Group, 113-142.
Guinea,T., Wu,M.,Miller,I., Purvine,O., Yi,C.,Eng,J.,&Lee,K. (2003). Proteomic analysisof Pseudomonasaeruginosagrownundermagnesiumlimitation.Journal ofthe American SocietyforMass Spectrometry, 14(7),742–51.
Gullberg,E.(2014). Theriseandspreadofantibioticresistance–Resistancemechanismsin bacteria. Available: http://www.reactgroup.org. Uppsala University, Sweden. Last accessed July2015.
Gupta,A.,Naraniwal,M.,&Kothari,V.(2012).Modernextractionmethodsforpreparation of bioactiveplant extracts, 1(1), 8-26.
Gutierrez, P., & Baez, G. (2008).Identification ofiridoid and sesquiterpenes fromBuddleia parviflorabyNMRspectra. Chemistryof NaturalCompounds., 44 (1), 29-31.
Gygi,P.,Corthals,L.,Zhang,Y.,Rochon,Y.,&Aebersold,R.(2000). Evaluationof two dimensional gel-electrophoresis-based proteomeanalysisttechnology.Proc. Nad. Acad. Sci.USA., 97, 9390-9395.
Handa, S.(2008).AnOverviewofExtractionTechniquesfor MedicinalandAromatic Plants.In:Khanuja,P.,Longo,G.,& Rakesh,D.ExtractionTechnologiesforMedicinal andAromatic Plants.Trieste,Italy:Earth,EnvironmentalandMarineSciencesand TechnologiesInternational Centrefor ScienceandHigh Technology,21-54.
Hardy,J.(2004).MethicillinresistantStaphylococcusaureusinthecriticallyill.British
Journal of Anesthesia, 92(1), 121–130.
Harry, R. (2005). Centella asiatica habit. Available:
Last accessed
30/08/2015.
Harun,I.,Ahmad,F.,Abdull,S.,&Sule,A.(2011). Apreliminarystudyonantimicrobial activity ofImperatacylindrica. BorneoJournalofResourceScienceandTechnology,1 (1), 63-66.
Harvey,L.(2008).Naturalproductsindrugdiscovery.DrugDiscovery Today,13(19-20),
894-901.
Hecker,M.,Becher,D.,Fuchs,S.,& EngelmannS.(2010).Aproteomicviewof cell physiologyand virulenceofStaphylococcus aureus,Int JMed Microbiol., 300, 76-87.
Hecker,M.,Engelmann,S.,& Cordwell, J. (2003). ProteomicsofStaphylococcusaureus- currentstateandfuture challenges. JournalofChromatography.B,Analytical Technologies in theBiomedical andLifeSciences, 787(1), 179–95.
Hellen,G.,Molly,M.,Suraj,P.,Sumanth,G.,Jordan,L.,Devra,B.,Andrea,W.,&Ramanan L.(2015). Thestateoftheworld’santibiotics.Washington,D.C.:CenterforDisease Dynamics, Economics&Policy, 14-24.
Henzel, T. Billeci, J., Stults, S.,Wong, C&Watanabe, C. (1993).Identifyingproteins from two-dimensionalgelsby molecularmasssearching ofpeptide fragmentsinprotein sequencedatabases. Proc NatlAcad Sci USA, 90,5011-5.
Hewick,M., Lu,Z., &Wang,H.(2003).Proteomicsindrugdiscovery.AdvancesinProtein
Chemistry, 65(3), 309-42.
Holkar,S.,Rokade,D.,Yadav,R.,&Daphal,N.(2012).DeterminationofAssay andPeak Purity EvaluationofAcyclovirandValacyclovirby RP-HPLCMethod.International Journal of Theoretical& Applied Sciences, 4(2),56–65.
Holzgrabe,U.,Diehl,W.,&Wawer,I.(1998).NMRspectroscopy inpharmacy.Journalof
Pharmaceutical andBiomedical Analysis, 17(4-5), 557–616.
Hong-Yu,X.,Lei,J.,Li-Ji, J.,Xiao-Yu,L.,Peng,Z.,&Yong-Sheng,M.(2009).Aucubin preventslossofhippocampalneuronsandregulatesantioxidativeactivity indiabetic encephalopathyrats.Phytother. Res. 23, 980–986.
Hsu, Y., Kuo, P.,Lin,L.,&Lin, C. (2005). Asiatic acid, a triterpene, induces apoptosis and cellcycle arrestthroughactivationofextracellular signal-regulatedkinase andp38 mitogen-activatedproteinkinase pathwaysin humanbreastcancercells. Journalof Pharmacologyand Experimental Therapeutics, 313(1), 333–344.
Hu,L.,PaulJ.,&Gu,J.(2012).Proteintargetdiscoveryofdruganditsreactiveintermediate metabolite byusingproteomicstrategy. Acta PharmaceuticaSinicaB, (2),126–136.
Huaiyu,H.,Poudel,S.,Muruganujan,A.,Casagrande,T.,&Thomas,D.(2016).PANTHER version10:expandedproteinfamiliesandfunctions,andanalysistools.Nucleic Acids Res, 44 (1),336–42.
Huang,S.,Chiu,S.,Chen,J.,Hou,C.,Sheu,J.,Lin,C.,Shie,H.,&Huang,J.(2011).
Antinociceptiveactivitiesandthemechanismsofanti-inflammationofAsiaticacidin mice. Evidence-Based Complementaryand AlternativeMedicine, 1–10.
Huang,W.,Lempicki,R.,&Sherman,T.(2009).Systematicandintegrativeanalysisoflarge genelistsusingDAVIDbioinformatics resources.NatureProtocols, 4(1),44–57.
Huang, W., Sherman,T.,Kir, J.,Liu,D., Bryant,D.,&Lempicki,A.(2007). DAVID Bioinformatics Resources:Expanded annotationdatabaseandnovelalgorithms tobetter extract biologyfrom largegenelists. NucleicAcids Research, 35(2), 169–175.
Hughes,D.,&Karlen,A.(2014).Discoveryandpreclinicaldevelopmentofnewantibiotics.
Upsala Journal of Medical Sciences, 119(2), 162–9.
Ignat,I.,Volf,I.,&Popa,I.(2011).Acriticalreviewofmethodsforcharacterisationof polyphenoliccompounds in fruits and vegetables.Food Chemistry, 126(4),1821–1835.
Ismail,H.,Samah,A.,&Sule,A.(2011).APreliminaryStudyonAntimicrobialActivityof
Imperata cylindrica.Borneo J. Resour. Sci. Tech, 1, 63–66.
Jackson,P.,Thornley,J.,&Thompson,J.(1985).Astudy by highresolutiontwo- dimensionalpolyacrylamide gelelectrophoresisof relationshipsbetweenNeisseria gonorrhoeae and other bacteria. Journal of GeneralMicrobiology, 30, 3189-201.
Jacob,P.,&Shenbagaraman, S.(2011).Evaluationofantioxidantandantimicrobial activities ofthe selectedgreen leafyvegetables.International Journal, 3(1), 148–152.
Jadhav, D., Rekha,N., Gogate, R.,&Rathod,K. (2009). Extraction ofvanillin from vanilla pods:Acomparisonstudy ofconventionalSoxhletandultrasound-assistedextraction.J. Food Eng., 93, 421–426.
Jain,D., Jain, S.,Jain,D.,&Amin,M.(2008).Simultaneousestimationofmetformin hydrochloride,pioglitazonehydrochloride,andglimepirideby RP-HPLCintablet formulation. Journalof Chromatographic Science,46, 501–504.
Jamil,M.,Ulhaq, I.,Mirza, B., &Qayyum,M.(2012). Isolationofantibacterialcompounds fromQuercusdilatataL.throughbioassay-guidedfractionation.AnnalsofClinical MicrobiologyandAntimicrobials, 11(1), 11.
Jew,S.,Yoo.H.,Lim,Y.,Kim,H.,Mook-Jung,I.,Choi,H.,Jung,H.,&Park,G.(2000).
Structure-activityrelationshipstudyofAsiaticacidderivativesagainstbeta-amyloid(A
beta)-induced neurotoxicity. BioorgMed ChemLett, 10,119-121.
Jhanker, M., Mohammad, F., Kadir, I., &Rubaiyat, H. (2012). Proteomics in Drug
Discovery. Journal of Applied Pharmaceutical Science,2 (8), 1 12.
Ji,F.,Li,J.,&Zhang,Y.(2009).Naturalproductsanddrug discovery.Canthousandsof yearsofancientmedicalknowledgeleadustonewandpowerfuldrug combinationsin the fight againstcancer and dementia?EMBO Reports, 10 (3), 194–200.
Ji,Q.,Zhu,F.,Liu,X.,Li,Q.,&Su,B.(2015).RecentAdvanceinApplicationsof Proteomics Technologies on Traditional ChineseMedicineResearch.Evidence-Based Complementaryand AlternativeMedicine, 13.
Jiao,C.,Qiao,S.,Cui,D.,&Ma,J.(2011).ContentDeterminationofBifendateinImperata
Cylindricalfrom Different Regions byHPLC. China KnowledgeInfrastructure,6, 1-5.
Jing,Y., Wang,G.,Ge,Y.,Xu,M.,& Gong,Z.(2015).Synthesis,anti-tumorandanti- angiogenicactivityevaluationsofAsiaticacidaminoacidderivatives.Molecules,20(4),
7309–7324.
Johari, J., Kianmehr, A., Mustafa, R., Abubakar,S., &Zandi,K. (2012).Antiviralactivity ofbaicaleinandquercetinagainsttheJapaneseencephalitisvirus.InternationalJournal of MolecularSciences, 13(12), 16020–16045.
John, T. (2013). Imperata cylindrica, in the rain. Available:
http://www.flickr.com/photos/31031835@N08/8665943029/.Last accessed 30/08/014.
John,W.(2002). SDSPolyacrylamide Gel Electrophoresisof Proteins. In: John M.Walker.
TheProtein Protocols Handbook.New Jersey: HumanaPressInc., 57-317.
Johnson, A.P. (2011).Methicillin-resistantStaphylococcusaureus:TheEuropean landscape. TheJournal of Antimicrobial Chemotherapy, 66 (4), 43–48.
Jungblut,R.(2001). Proteome analysisof bacterialpathogens.MicrobesandInfection/ InstitutePasteur, 3(10),831–40.
Kaake,M.,Wang,X.,& Huang,L.(2010). Profiling ofproteininteractionnetworksof proteincomplexesusingaffinity purificationandquantitativemassspectrometry. Molecular&CellularProteomics: MCP, 9(8), 1650–1665.
Kalita, D., &Saikia, J. (2012).Ethnomedicinal, antibacterial andantifungal potentialityof CentellaAsiatica,Nerium IndicumandCuscutareflexa-widely usedinTiwaTribe of Morigaon district ofAssam,India.Inter. Journalof Phytomedicine, 4(3),380–385.
Kambiz,M.andSylvia,D.(2010).Massspectrometry-basedproteomicsinthelifesciences:
areview. Journal of Paramedical Sciences(JPS), 1 (2), 53-78.
Kang,Y.,Yi,Y.,Zhang,C.,Wu,S.,Shi,C.,&Wang, X. (2013). Bioassay-guidedisolation andidentificationofactivecompoundsfrom Macleayamicrocarpa(Maxim)againstfish pathogenicbacteria. AquacultureResearch, 44(8), 1221–1228.
Karpievitch,V.,Polpitiya,D.,Anderson,A.,Smith,D.,& Dabney,R.(2011).Liquid chromatography-massspectrometry-basedproteomics:Biologicaland technological aspects. Annals ofApplied Statistics, 4(4), 1797–1823.
Katiyar,C.,Gupta,A.,Kanjilal,S.,&Katiyar,S.(2012).Drugdiscoveryfromplantsources: An integrated approach. Ayu, 33(1), 10–9.
Katrijn, B., &Arthur, A.(2009). Antimicrobial resistanceinbacteria. Cent.EUR. J.Med. 4 (2), 141-155.
Kaushik,P.,& Dhiman,K.(1999).MedicinalplantsandrawdrugsofIndia.Dehra Dun, India, 635.
Kazmierczak, Z., Gorski, A., &Dabrowska, K. (2014). Facing antibiotic resistance:
Staphylococcus aureus phages as amedical tool.Viruses, 6(7), 2551–70.
Khurram,M.,Lawton, L.,Iriti,A.,Khan,M.,&Rahman,S.(2015).RapidBioassay-Guided IsolationofAntibacterial ClerodaneTypeDiterpenoidfromDodonaeaviscosa(L.)Jaeq. International Journal ofMolecularSciences, 16 (9), 20290–20307.
Kisangau,P.,Hosea,M.,Joseph,C.,&Yaruu, M.(2007).Invitroantimicrobialassay of plants used in traditionalmedicine in Bukobarural district, Tanzania.Afr. J.Traditional.
4 (4), 510 – 523.
Klose,J.(1975).Proteinmappingby combinedisoelectricfocusingandelectrophoresisof mousetissue.Anovelapproachtotestingforinducedpointmutations inmammals. Humangenetik. 26, 231-243.
Kohanski,A.,Dwyer,J.,& Collins, J.(2010).Howantibioticskillbacteria:fromtargetsto networks. NatureReviews. Microbiology, 8(6), 423–435.
Kohler,C.,Wolff,S.,Albrecht,D.,Fuchs,S.,Becher,D.,Buttner,K.,etal.(2005).Proteome analysesofStaphylococcusaureusingrowing andnon-growing cells:aphysiological approach.Int. J. Med. Microbiol. 295, 547–565.
Kothari, V.,Gupta,A.,&Naraniwal, M.(2012).Comparativestudyof various methods for extraction ofantioxidant and antibacterial compounds from plant seeds. Journal of Natural Remedies,1(2),162-173.
Kraus, N.(2008).Lowhangingfruitininfectiousdiseasedrugdevelopment.Current
Opinion in Microbiology, 11,434-438.
Krystyna,K., Graham,A.,&Webb,A.(2010).Theoreticalandphysicalaspectsofnuclear shielding.In:G. A. WebbandK. Kamieńska-Trela Nuclear Magnetic Resonance: Volume 39. Cambridge,UK: Theroyal societyofchemistry, 42-69.
Kumar,S.,&Pandey,K.(2013).Chemistry andbiologicalactivitiesofflavonoids:An overview. TheScientific WorldJournal, 230.
Kumar,T.,Panda,D., Nanda, N., &Khuntia, S.(2010).Evaluation ofAntibacterial, AntifungalandAnthelminticActivityof MorindacitrifoliaL.(Noni). International Journal of PharmTech Research, 2 (2), 1030-1032.
Kupiec, T. (2004). Quality-Control Analytical Methods: High-Performance Liquid
Chromatography.Inter. Journal of PharmaceuticalCompounding, 8(3), 223–227.
Kuroda,Y.,Mimaki,H.,Harada,S.,&Sashida,Y.(2001).Fivenewtriterpeneglycosides from Centella AsiaticaL.Natural Medicines,55 (3), 134-138.
Laemmli,K.(1970).Cleavageofstructuralproteinsduring theassembly oftheheadof bacteriophageT4. Nature, 227, 680–5.
Lambert,J.(2001).Advancesindisinfectiontestingandmodelling.JournalofApplied
Microbiology, 91(2), 351–63.
Lambert,W.,&Lambert,R.(2003).Amodelfortheefficacyofcombinedinhibitors.Journal of Applied Microbiology, 95(4), 734-743.
Landecker,H.(2015).AntibioticResistanceandtheBiologyofHistory.Body&Society,
1–34.
Lane,S.(2005)Massspectrometry-basedproteomicsinthelifesciences.Cell.Mol.Life
Sci., 62, 848-869.
Latterich,M.,Abramovitz,M.,&Leyland-Jones,B.(2008). Proteomics:new technologies and clinical applications.European Journal of Cancer, 44 (18), 2737–41.
Laubacher,E.,&Ades,E.(2008).TheRcsphosphorelay isacellenvelopestressresponse activatedby peptidoglycanstressandcontributestointrinsicantibioticresistance.J Bacteriol., 190, 2065-2067.
Laureti,L.,Matic,I.,&Gutierrez,A.(2013).BacterialResponsesandGenomeInstability
Induced bySubinhibitoryConcentrations of Antibiotics. Antibiotics, 2(1), 100–114.
Lawrence,H.,&Ferry,G. (2006). Steady-statekinetic analysisof phosphotransacetylase from Methanosarcina thermophila. Journal of Bacteriology, 188(3), 1155–8.
Lee,R.,Lee,H.,Park,S., Jeong,C.,&Lee,H.(2015).Quantitativeproteomicview associatedwithresistancetoclinically importantantibioticsinGram-positivebacteria:a systematicreview.Front.Microbiol., 6,828.
Lee,S., Jin, Q.,Beak,M.,Lee,S.,& Kim,A.(2003).InhibitionofultravioletA-modulated signalingpathways by AsiaticacidandursolicacidinHaCaThumankeratinocytes. European Journal of Pharmacology, 476, 173–178.
Lee, W.,Kho,S.,&Lee,G. (1999). The effectsof iridoidcompoundsonwound healing.J KoreanAcadOral Med.(24), 137-142.
Li,J.,Huang, X., Du,X.,Sun,W.,&Zhang, Y. (2009).Studyof chemical compositionand antimicrobialactivityofleavesandrootsofScrophularianingpoensis.NatProdRes.,23 (8),775-80.
Li,M., &Xu,Z. (2008).Quercetinin alotusleaves Extractmayberesponsiblefor antibacterialactivity. Archives ofPharmaceuticalResearch, 31(5), 640–644.
Li,Y.,Welbeck,E.,Wang,F., Liu,Q.,Yang, B., Chou,X.,&Wang,T.(2015).Auniversal quantitative1Hnuclearmagneticresonance(qNMR)methodforassessingthepurity of dammarane-typeginsenosides. Phytochemical Analysis, 26(1), 8–14.
Lima,B.,Pinto,S.,Ribeiro,M.,Lima,A.,Viana,C.,Junior,G.,&Franco,L.(2013).
Bacterial resistancemechanism: What proteomicscan elucidate.FASEBJournal, 27(4),
1291–1303.
Lindner,E.,Swearingen,E.,Harupa,A.,Vaughan,M.,Sinnis,P., Moritz,L.,& Kappe,S. (2013).TotalandPutativeSurfaceProteomicsof MalariaParasiteSalivary Gland Sporozoites. Molecular&CellularProteomics:MCP, 12(5), 1127–1143.
Liu,J.,He,T.,Lu,Q., Shang,J., Sun,H., &Zhang,L.,(2010).Asiatic acidpreservesbeta cellmass andmitigateshyperglycemiainstreptozocin-induced diabeticrats.Diabetes / Metabolism Researchand Reviews, 26, 448–454.
Liu, P., Duan,Q., Pan,Q., Zhang, W., Yao,Z.(2006). Triterpenesfromherb ofPotentilla chinesis. ZhongguoZhongYaoZaZhi, 31, 1875–1879.
Liu,W.,Liu,C.,&Mong,M.(2015).AntibacterialeffectsandactionmodesofAsiaticacid.
BioMedicine, 5 (3), 16.
Liu,X.,Hu,Y., Pai, J.,Chen,D.,&Lam,H.(2014).Label-free quantitative proteomics analysisofantibioticresponseinStaphylococcusaureustooxacillin.JournalofProteome Research, 13,1223–1233.
Liu,X.,Zhang,B.,Chou,G.,Yang,L.,&Wang,Z.(2012a).Chemicalconstituentsfrom
Imperata cylindrica. PubMed – Medline, 37 (15),2296-300.
Liu,X.,Zhang,B.,Chou,G.,Yang,L.,&Wang,Z.(2014b).Fournewcompoundsfrom
Imperata cylindrica.Journalof Natural Medicines– Springer, 68(2), 295-301.
Livermore,M.(2000).Antibiotic resistance instaphylococci.Internationaljournalof antimicrobial agents, 16(1), 3–10.
Lundgren,I.,Hwang,W.,&Han,K.(2010).Roleofspectralcounting inquantitative proteomics. Expert review ofproteomics, 7, 39-53.
Luong,T.,Ouyang,S.,Bush,K.,&Lee,Y.(2002).Type1capsulegenesofStaphylococcus aureus arecarried in astaphylococcal cassette chromosomegeneticelement. JBacterial,
184, 3623-3629.
Luzhetskyy,A., Pelzer,S.,&Bechthold,A.(2007).The future ofnaturalproductsasa sourceof new antibiotics. Current Opinion inInvestigational Drugs, 8 (8),608-613.
Lynne, V., &McFarland,S.(2000).Normalflora:diversityand functions.Microbial
Ecologyin Health and Disease, 12 (1), 193–207.
Maalik,A.,Khan,A.,Mumtaz,A.,Mehmood,A.,Azhar,S.,Atif,M.,Tariq,I.(2014).
PharmacologicalApplicationsofQuercetinanditsDerivatives:AShortReview.TropJ Pharm Res Tropical Journal of Pharmaceutical Research, 13(139), 1561–1565.
MacDonald, E. (2004). Cogongrass (Imperata cylindrica) Biology, Ecology, and
Management. Critical Reviews in Plant Science, 23, 367-380
Mahajan,S.,&Singh,P.(2013).Determiningandreportingpurity oforganicmolecules: WhyqNMR. MagneticResonancein Chemistry, 51(2), 76–81.
Makoto,K., Toshiko,O.,Ikuo,U.,Tadashi,B.,Harumi,Y.etal.(2001). Whole genome sequencingof meticillin-resistant Staphylococcusaureus. TheLancet. 357,1225-1240.
Malheiros,A., Filho,C., Schmitt,B.,Yunes,A., Escalante,A., Svetaz,L.,Zacchino, S.,& Monache,D.(2005).Antifungalactivity ofdrimanesesquiterpenesfromDrimys brasiliensisusingbioassay-guidedfractionation.JPharmPharmaceutSci.,8(2),335-
339.
Malviya,R.,Bansal,V.,Pal,P.,&Sharma,K.(2010).Highperformanceliquid chromatography: A short review.Journal of Global PharmaTechnology,2 (5), 22-26.
Mandana,B., Russly, A., Farah, S., Ali, G.,Liza, M., Jinap, S., Azizah H.,&ZaidulC. (2011). Comparison of different extraction methods forthe extraction ofmajor bioactive flavonoidcompoundsfromspearmint (MenthaspicataL.) leaves.Food andbioproducts processing, (89),67–72.
Mann,M.,Hojrup,P.& Roepstorff,P.(1993).UseofMSmolecularweightinformationto identifyproteins in sequencedatabases.BiolMass Spectrum,22, 338-45.
Marderosian,D.,&Liberti,L.(1988).Naturalproductmedicine,GeorgeF.Stickley Co., Philadelphia,431.
Maria,J.,Luis,M., Luis,A.,&Paulina,B.(2012).Anti-InfectiveFlavonoids:AnOverview.
In:GoutamBrahmachari.BioactiveNaturalProducts:OpportunitiesandChallengesin
Medicinal Chemistry. Singapore: World ScientificPublishingCo. Pte.Ltd., 443-474.
Maria,R.,Rosa,G.,Manez,S.,&Rios,L.(1994).Structuralconsiderationsontheiridoids as anti-inflammatoryagents. Plant Med., 60, 232-234.
Marissa,M.(2010).SurveyofPhytochemicalDiversityofSecondaryMetabolismin
Selected Wild Medicinal Plants. Ethnobotanical leaflets., 14,616-25.
Marton,J.,DeRisi,L.,Bennett,A.,Iyer,R.,Meyer,R.,Roberts,J.,&Friend,H.(1998).
DrugtargetvalidationandidentificationofsecondarydrugtargeteffectsusingDNA
microarrays. Nat.Med., 4(11), 1293–1301.
Materska,M.,Perucka,I., Stochmal,A.,Piacente,S.,& Oleszek,W.(2003).Quantitative andQualitativeDeterminationof Flavonoids and Phenolic AcidDerivativesfrom PericarpofHotPepperFruitCv.BronowickaOstra.Polish JournalOdFoodand Nutritional Sciences, 12 (53), 72–76.
Matsuda,T.&Morikawa,U.(2001).MedicinalFoodstuffs.XXVII.1)SaponinConstituents of GotuKola (2): StructuresofNew Ursane- andOleanane-Type Triterpene Oligoglycosides,CentellasaponinsB,C,andD,fromC.asiaticaCultivatedinSriLanka. Chemical and Pharm. Bulletin, 49(10), 1368–1371.
Mayers,A.,Lerner,M., etal.(2009).AntimicrobialDrugResistanceC:Clinicaland
Epidemiological Aspects, vol. 2, Springer Dordrecht Heidelberg,London,681–1347.
Ma-Zhang,Y.,Zhu,D.,&Lou,Y.,(2009). Protective effectsofAsiatic acidagainstd- galactosamine/lipopolysaccharide-inducedhepatotoxicity inhepatocytesandkupffer cellsco-culturedsystemviaredox-regulatedleukotrieneC4synthaseexpressionpathway. European Journal of Pharmacology, 603, 98–107.
McCormack,A.,Eng,K.,&Yates,I.(1994).Anapproachtocorrelatetandemmassspectral dataofpeptideswithaminoacidsequencesinaproteindatabase.JournaloftheAmerican Societyfor Mass Spectrometry,5, 976-989.
Megger,A.,Bracht,T.,Meyer,E.,&Sitek,B.(2013).Label-freequantificationinclinical proteomics.BiochimicaetBiophysicaActa-ProteinsandProteomics,1834(8),1581–
1590.
Mei,Z.,Steven,G.,etal. (2011).AntioxidantPropertiesofQuercetin.AdvExp MedBiol.,
701 (1), 283-289.
Mendonça-Filho,R.(2006).Bioactive phytocompound:Newapproachesinthe phytosciences. Medicinal Plants into Drugs. Wiley-VCH, 1–24.
Mengiste,B., Hagos,Y.,& Moges,F.(2014).InvitroAntibacterialScreening ofExtracts from Selected EthiopianMedicinal Plants. MomonaEthiopian,6 (1), 102–110.
Mesbah, K.,Khalifa,I.,El-Gindy,A.,&Tawfik,A. (2005).HPLC determination of certain flavonoids and terpenelactones in selectedGinkgo BilobaL. phytopharmaceuticals. Farmaco, 60, 583-590.
Mestrelab Research. (2015). MestreNova Manual. Available:
http://mestrelab.com/software/mbook/help/manual/.Last accessed 13th Mar2016.
Michael,W.,&John, Y.(2000).Newmethodsofproteomeanalysis:multidimensional chromatographyandmassspectrometry. Proteomics:ATrendsGuide,100(1),1471-
1931.
Mihaylova,D.,& Schalow,S.(2013).Antioxidantandstabilizationactivity ofaquercetin- containing flavonoidextract obtained fromBulgarian SophorajaponicaL.Brazilian Archives ofBiologyandTechnology, 56(3), 431–438.
Militao, G., Pinheiro, S.,Dantas,I.,Pessoa, C., Moraes, M.,Costa-Lotufo,L.,Lima,M.,&Silveira, E. (2007).Bioassay-guidedfractionationof pterocarpansfromrootsof HarpalycebrasilianaBenth. Bioorgan Med Chem., 15, 6687–6691.
Miller, R., Munita, M., &Arias, A. (2014). Mechanisms of antibiotic resistance in
enterococci. Expert review of anti-infectivetherapy,12(10), 1221–36.
Mirza, P.(2012). Quantitativemassspectrometry-basedapproachesincardiovascular research. Circulation:CardiovascularGenetics, 5(4), 1–8.
Mohamed, A., Abdel-Lateff, A.,Fouad, A., Sabrin, M.,Ibrahim, C., Elkhayat, S., &Okino, T.(2009).ChemicalCompositionandHepato-protectiveactivity ofImperatacylindrica Beauv. PharmacognosyMagazine,4 (17), 28-36.
Monaghan, L., &Barrett, F. (2006). Antibacterial drug discoverythen, now and the genomicsfuture.Biochem Pharmacol., 71, 901–909.
Monica, S., Vlado, D.,Bridget, W., &Paul,A.C., (2013).Target identification and mechanismof action in chemical biologyand drugdiscovery.NatureChemical Biology,
9 (1), 232–240.
Monteiro,C.,Cruz, M.,Cantizani,J., Moreno,C.,Tormo,R.,Mellado,E.,&VicenteF. (2012).Anewapproachtodrug discovery:high-throughputscreeningofmicrobial naturalextractsagainstAspergillusfumigatususing resazurin.JournalofBiomolecular Screening, 17 (4), 542–9.
Moreno,S.,Scheyer,T.,Romano,C.,& Vojnov, A.(2006).Antioxidantandantimicrobial activitiesofrosemary extractslinkedtotheirpolyphenolcomposition.FreeRadic.Res.,
40 (2), 223-231.
Murugan,M.,& Mohan,V.(2011).Evaluationofphytochemicalanalysisandantibacterial activityof Bauhinia purpureaL.and Hiptage benghalensisL. Kurz.,1 (9),157–160.
Nayak,K.,Suchitra,V.,&Nanda,A.(2015).Antibacterialpotency ofhydro-alcoholleaf extractofMorindacitrifoliaL.(Noni) by Soxhletextractionmethod.DerPharmacia Lettre, 7 (4), 51–54.
Ncube, S., Afolayan,J.,&Okoh,I.(2008).Assessmenttechniquesof antimicrobial propertiesof naturalcompoundsof plantorigin:currentmethodsandfuture trends. African Journal ofBiotechnology, 7(12), 1797–1806.
Nicolino,L.,Crescenzo,G.,Lai,R.,& Milillo, A.(1997).Investigationontheextraction andconcentrationof oleuropeinandflavonoidsinOleaEuropeaL.basedproducts. Pharm. Pharmacol.Lett.,7 (1), 27-30.
Nikaido,H.(2009).Multidrugresistanceinbacteria.AnnualReviewofBiochemistry,78(2),
119–46.
Nilsson, T., Matthias, M., Ruedi,A., John, Y., Amos, B., &John, J.(2010).Mass spectrometryinhigh-throughputproteomics:readyforthebigtime.Naturemethods,7,
681-5.
Nugroho,A.,An,J.,Song,M.,&Park,H.(2015).Isoeugenol,aNovelNitricOxideSynthase
InhibitorIsolatedfrom therhizomes ofImperata cylindrica. Molecules,20(12), 21336–
21345.
O’Farrell, H. (1975). High-resolution two-dimensionalelectrophoresis of proteins.J.
Biol.Chem., 250, 4007-4021.
Olgica,S.,Ivana,R.,Sava,V.,&Ljiljana,C.(2012).AntibacterialActivity ofNaturally Occurring Compoundsfrom Selected Plants.In:VaraprasadBobbaralaAntimicrobial agents. Croatia:InTech.,1-24.
Olivier,P.,&Matthias,H.(2008).Drugdiscovery anddevelopmentwithplant-derived compounds.In:Frank Petersen and ReneAmstutzProgress in DrugResearch,45-118.
Omezine,A.&Skiri-Harzalla,F.(2009).Regenerativecapacity ofspeargrass(Imperata cylindricaL.). P. Beauv.Pak. J.Weed Sci., 15 (1),53-69.
Orhan,E. (2012). Centella Asiatica(L.) Urban:From traditionalmedicine tomodern medicinewithneuroprotectivepotential.Evidence-BasedComplementary and Alternative Medicine, 264.
Oveland,E.,Muth,T.,Rapp,E.,Martens,L.,Berven,S.,&Barsnes,H.(2015).Viewingthe proteome: How to visualizeproteomics data. Proteomics, 15(8), 1341–1355.
PanJ.,Kai,G.,Yuan,C.,Zhou,B.,Jin,R.,&Yuan,Y.(2007).Separationanddetermination of madecassicacidinextractsof CentellaAsiaticausinghighperformance liquid chromatography withβ-cyclodextrinasmobilephaseadditive.ChineseJournalof Chromatography, 25,(3),316–318,
Pan, Y., Cheng, T., Wang, Y., &Bryant, S. (2014). Pathway Analysis for Drug
Repositioning Based onPublicDatabaseMining.Chem.Inf. Model., 54, 407−41.
Pandey,A., &Mann,M.(2000).Proteomicstostudygenesand genomes.Nature,405,837-
846.
Pandey,K.,&Kumar,S.(2013).PerspectiveonPlantProductsasAntimicrobialsAgents: A Review. Pharmacologia, 4 (7), 469-480.
Pandit,S.,Kumar,M.,Ponnusankar, S.,Pal,C.,& Mukherjee,K.(2011).RP-HPLC-DAD for simultaneousestimationofmahanineandmahanimbineinmurrayakoenigii. Biomedical Chromatography, 25(9), 959–962.
Pappin,J.,Hojrup,P.,&Bleasby,A.(1993).Rapididentificationofproteinsby peptide-mass fingerprinting. CurrBiol., 3, 327-32.
Parka,V.,Vignesh,M.,Selvakumar,K.,Mohamed,M.,&Ruby J.(2012).Antibacterial Activityof Aerial Parts of Imperata cylindrica (L) Beauv.International Journal of Pharmaceutical Sciencesand DrugResearch,4(3), 209-212.
Parmar, K.,Mahato,T.,Shah, M.,&Acharya,A. (2014). Qualitativeand quantitative ApplicationofNMRinRilmenidinedihydrogenphosphateAPI anditsrelatedimpurity andcorrelationwithalternatetechnique.InternationalJournalofPharmaceuticalSciences Review and Research, 26(2), 6–12.
Parvathy,G.,Padma,R.,Renjith,V.,Kalpana,P.,&Saranya,S.(2012). Phytochemical ScreeningandAnalysisPolyphenolicAntioxidantActivity ofMethanolicExtractof Imperata Cylindrica, 23 (1), 60–64.
Parvathy,G.,Padma,R.,Renjith,V.,Kalpana,R.,&Saranya,S.(2012). Phytochemical screeningandanthelminticactivityofmethanolicExtractofImperatacylindrica. IntJ Pharm Pharm Sci., 4 (1),232-234.
Patel,S.,&Korotchkina,G.(2006).Regulationofthepyruvatedehydrogenasecomplex.
Biochemical SocietyTransactions, 34(2), 217–222.
Paul,M.,&Beena,K.(2011).AntibacterialactivityofSauropusandrogynus(L.)Merr.
Internat. J. Plant Sci., 6 (1), 189-192.
Paul,M.,&Dewick,S.(2009).MedicinalNaturalProductsaBiosyntheticApproach.3rd ed. Nottingham, UK: A John Wileyand Sons,Ltd., Publication,2-39.
Pauli,F.,Chen,N.,Simmler,C., Lankin,C.,Godecke,T.,Jaki,U.,&Napolitano,G.(2014).
Importanceofpurityevaluationandthepotentialofquantitative1HNMRasapurity assay. Journal of Medicinal Chemistry, 57(22), 9220–9231.
Pauli, F., Jaki,U.,&Lankin,C. (2005).Quantitative 1HNMR.Developmentand Potential of aMethod forNatural Products Analysis. Journal of natural products,68(1), 133-149.
Paulsen, S. (2010). Highlights through the historyof plant medicine. In: Berghof A.
Bioactivecompoundsinplants–benefitsandrisksformanandanimals.Oslo,Norway: TheNorwegian Academyof ScienceandLetters,18-30.
Pawlikowska-Pawlega,B.,Gruszecki,W.I.,Misiak,L.,Paduch,R.,B.,etal.(2007).
Modification of membranes by quercetin, a naturally occurring flavonoid, via its incorporation in thepolarheadgroup.Biochim Biophys Acta., 1768(9), 2195-2204.
Peffers,J.,McDermott,B.,Clegg,D.,&Riggs,M.(2014).Comprehensiveproteinprofiling ofsynovialfluidinosteoarthritisfollowing proteinequalization.Osteoarthritisand Cartilage, 23, 1204–1213.
Peng,S.,Peng,M.,Bu,X.,Wu,G.,&Hu,W.(2010).ExtractionandSeparationofAucubin fromtheLeaveofEucommiaulmoidesinAqueousTwo-phaseSystem. NaturalProduct Research&Development,22 (2), 264.
Perez-Vizcaino,F.,&Duarte,J.(2010).Flavonolsandcardiovasculardisease.Mol.Aspects.
Med., 31 (6), 478-94.
Pewarna,S.,Larut,M.,& Tradisional,S.(2015).Potentialsourcesfor lipid-solublefood colorants from selectedMalaysian traditional vegetables, 19(1), 268–274.
Phillipson,J.(2001).Phytochemistryandmedicinalplants.Phytochemistry,56 (3),237–43. Phuong, T. (2010).Sauropus androgynus, Star Gooseberry, Sweet leaf (Red flower).
Available:http://www.flickr.com/photos/phuonglovejesus2782010/5615280217/in/phot ostream/.Last accessed 22/8/2014.
Piddock,V.(2006).ClinicallyRelevantChromosomallyEncodedMultidrugResistance
EffluxPumps in Bacteria.ClinicalInfectious Diseases, 19 (2), 382–402.
Pieper,R.,Gatlin-Bunai,L.,Mongodin,F.,Parmar, P.,Huang,T.,Clark, J.,&Peterson,N. (2006).Comparative proteomic analysisofStaphylococcusaureusstrainswith differences inresistancetothe cellwall-targeting antibiotic vancomycin. Proteomics, 6 (15), 4246–4258.
Prabu, L., &Suriyaprakash, K. (2010). Impurities and its importance in pharmacy.
International Journal of Pharmaceutical SciencesReview and Research, 3(2), 66–71.
Prathapa,B.,Akalanka,D.,SrinivasaG.,JohnsonaP.,&Arthanariswaranc,P.(2013).A Review-ImportanceofRP-HPLCinAnalyticalMethodDevelopment. Inter.journalof novel trends in pharmaceutical sciences,3(1), 15-23.
Queiroz,F.,Wolfender,L.,Atindehou,K.,Traore,D.,& Hostettmann,K.(2002).On-line identificationoftheantifungalconstituentsofErythrinavogeliibyliquidchromatography withtandemmassspectrometry,ultravioletabsorbancedetectionandnuclear magnetic resonancespectrometry combinedwithliquid chromatographicmicro-fractionation. Journal of Chromatography, 974(1-2), 123–134.
Rabilloud,T.,&Lelong,C.(2011). Two-dimensionalgelelectrophoresisinproteomics:a tutorial. Journal of Proteomics, 74(10), 1829-41.
Ragunathan, A., Ravi, L., &Ravi, L. (2015). Potential antibacterial drug targets for
QuercetinandRutin:AninsilicostudyusingAutoDock,DerPharmaciaLettre,7(11),
68–72.
Rahman,M., Hossain, S., Rahaman,A.,Fatima, N.,Nahar,T., &Uddin, B. (2013).
AntioxidantActivityofCentellaasiatica(Linn.)Urban:ImpactofExtractionSolvent
Polarity. Journal of Pharmacognosyand Phytochemistry, 1(6), 27–32.
Rahman,M.,Sayeed,M.,&Haque,M.(2012).Phytochemicalscreening,Antioxidant,Anti- AlzheimerandAnti-diabeticactivitiesofCentella Asiatica. Scholarsresearchlibrary,2 (4), 504–511.
Rakesh,S.(2012).Enzyme Inhibition:MechanismsandScope. In:RakeshSharmaEnzyme
Inhibition andBio applications,InTech., 3-36.
Ramachandran,V.,&Saravanan,R.(2013).EfficacyofAsiaticacid,apentacyclictriterpene onattenuating thekey enzymesactivitiesofcarbohydratemetabolisminstreptozotocin- induced diabeticrats. Phytomedicine, 20(3-4), 230–236.
Ramawat,G.,Dass,S.,&Mathur,M.(2009).HerbalDrugs:EthnomedicinetoModern
Medicine. Springer-Verlag Berlin Heidelberg. 540-543.
Rappsilber,J.,&Mann,M.(2002).Whatdoesitmeantoidentifyaproteininproteomics?
Trends in Biochemical Sciences, 27(2), 74–8.
Rates,M.(2001).Plantsassourceofdrugs.Toxicon:OfficialJournaloftheInternational
Societyon Toxicology, 39(5), 603–13.
Relman, A. (2002). Thehuman bodyas microbialobservatory. Nat Genet, 30, 131-133. Ribeiro,J.,Przybylski,D.,Yin,S.,Sharpe,T.,Gnerre,S.,Abouelleil,A.,etal.(2012).
Finished bacterialgenomes from shotgun sequencedata. Genome Res., 22,2270–2277.
Rishikesh,R.&Rahman,M.(2013).ThrombolyticactivityofCentellaAsiaticaleaves.
International Journal of Pharmacy, 3(2), 308–311.
Rivera,A.,Giono,S., Gonzalez,M.,Rodriguez,N.,& Cedillo,L.(2011).Antibacterial effectofMorindac.fruitjuiceagainstmycoplasmas.AnnalsofBio.Res.,2(3),491-497.
Rodriguez,N.,Menendez,N.,Tornero, J.,Amils,R.,&Fuente,V.(2005).Internaliron biomineralizationinImperatacylindrica,a perennialgrass:Chemicalcomposition, speciation and plant localization. New Phytologist,165(3), 781–789.
Rodriguez-Suarez,E.,andWhetton,A.D.(2013).The Applicationofquantification techniques in proteomicsforbiomedical research.Mass Spectrom. Rev., 32, 1–26.
Rogowska-Wrzesinska,A.,Le,B.,Thaysen-Andersen,M.,&Roepstorff,P.(2013).2Dgels stillhaveanichein proteomics. Journal of Proteomics, 88, 4–13.
Romika, D., Neeraj, A.,Kamal, R., &Manpreet, K. (2015).In Vitro Antimicrobial Activity of Spices and Medicinal Herbs against Selected Microbes Associated with Juices.International Journal of Microbiology, 1(1), 1-9.
Rong-huaL.,Shi-sheng,C.,Gang,R.,Feng,S.,&Hui-lian,H.(2013).PhenolicCompounds from Roots of I. cylindricavar. major. ChineseHerbal Medicines, 5 (3), 240-243.
Roy,C.,Barman,K.,&Shaik,M.(2013).CurrentUpdatesonCentellaAsiatica: Phytochemistry, Pharmacologyand Traditional Uses. Med Plant Res., 3 (4), 20–36.
Rybak,J.,&Plante,L.(2005)CommunityAssociatedMethicillin-ResistantStaphylococcus Aureus:MolecularAnalysisofCommunity –andHealthCare-AssociatedMRSA. Pharmacotherapy, 25 (1),74-85.
Sahoo, S.,Desai,H.,Bhatt,A., Shivramchandra,K.,&Kamath,V.(2015).1H qNMR ApproachforEstimationofaToxicCompound N,N-DimethylamineinMetformin Hydrochloride:An EquivalentEfficientMethodover Reversed PhaseDerivatization HPLC Method, 2(2), 442–443.
Sailaja,A., Somasubra,G.,Thumma, P.,Deepthi,N., &David,B.(2014). A Review on TroubleShootinginHPLCanditsSolutions.InternationalJournalofPharmaceuticaland Chemical Sciences, 3 (3), 625-635.
Salih,N., Salimon, J.,& Yousif,E.(2012).Synthesis,characterizationandantimicrobial activity ofsomecarbamothioyl-1,3,4-thiadiazolederivatives.InternationalJournalof PharmTech Research, 4(2), 655-660.
Saludes,P.,Garson, J.,Franzblau,G.,&Aguinaldo,M.(2002).Anttubercularconstituents fromthehexane fractionofMorindacitrifoliaL.Linn.(Rubiaceae),Phytotherapy Research, 16,683-685.
Samy,R.,Perumal,I.,&Vincent,T.(2011).AntimicrobialandPhytochemicalAnalysisof
Centella asiatica(L.). NaturePrecedings, 1, 1-6.
Sang, S.,Liu,G., He,K.,Zhu,N.,etal.(2003). New unusualiridoidsfromthe leavesof noni(MorindacitrifoliaL.)Showinhibitory effectonultravioletinducedtranscriptional activator protein-1(AP-1) Activity,Bioorganicand Med Chem., 11, 2499-2502.
Sarker, D., Latif, Z., &Gray, I. (2006). Methods in Biotechnology. Natural Products
Isolation. 2nd ed. Totowa, New Jersey: Humana PressInc., 1-27.
Sathyaraj,A.,&Satyanarayana,V.(2011).GradientRP-HPLCmethodforthedetermination ofPurity andAssay ofRaloxifenehydrochlorideinBulkDrug.ResearchJournalof Chemical Sciences, 1(2), 9–16.
Satyajit, D.,Zahid,L.,& Alexander,I. (2006). Natural ProductsIsolation. 2nd ed. Totowa, New Jersey: HumanaPressInc., 1-27.
Schaneberg,T.,Mikell,R.,Bedir,E.,& Khan, A.(2003).AnimprovedHPLCmethodfor quantitativedeterminationofsixtriterpenesinCentellaAsiaticaextractsandcommercial products. Pharmazie, 58, 381–384.
Scheele,A. (1975).Twodimensionalgelanalysisof soluble proteins.Characterisationof guineapig exocrinepancreaticprotein. J. Biol. Chem., 250, 5375-5385.
Seevaratnam,V.,Banumathi,P.,Premalatham,R.,Sundaram,P.&Arumugam,T.(2012).
Functional properties of Centella Asiatica L.: A review.International Journal of
Pharmacyand Pharmaceutical Sciences, 4 (5), 8-14.
Sefton, M. (2002). Mechanisms of Antimicrobial Resistance. Drugs, 62 (4), 557-566. Seidel,V.(2006).InitialandBulkExtraction.In:Sarker,S.D.,Latif,Z.&Gray,andA.I.
(eds.) Natural ProductsIsolation. New Jersey:HumanaPress, 27-47.
Selma,R., Lima,L.,Figueiredo,R.,&Kaplan,M.(2004).Plumbaginquantificationinroots ofPlumbagoscandensL.obtainedbydifferentextractiontechniques.Ann.Acad.Bras,
76 (3), 499-504.
Senthamarai, V., &Basker, A. (2012). Phytochemical Analysisand GC-MSprofilingin the leaves of Sauropus A.L.MERR.Int. J. DrugDev.&Res., 4 (1), 162-167.
Serafini,R.,Santos,C., Guimaraes,G.,Dos,A.,Conceicao,D.,Alves,A.,&SouzaA. (2011). MorindacitrifoliaL.LinnLeaf ExtractPossessesAntioxidantActivitiesand Reduces NociceptiveBehavior andLeukocyteMigration. Journal of Medicinal Food, 14 (10), 1159–1166.
Shaikh,S.,Fatima, J., Shakil,S., Rizvi, SyedD.,& Kamal,A.(2015).Antibioticresistance andextended-spectrumbeta-lactamases:Types,epidemiology andtreatment.Saudi Journal of Biological Sciences, 22(1), 90–101.
Shamnas,M.,Arya,S.,& Deepak,G.(2013).OptimizationofAntibiotic Chemotherapy:A Review. Thepharmainnovation journal, 2-3.
Shankar,S.,&Aravind,S.(2015).TraditiontoTherapeutics:Sacrificialmedicinalgrasses
DesmostachyabipinnataandImperata cylindricaofIndia, 14 (3), 156–170.
Sharma,K.,Singh,L.&Singh,S.,(2013).ComparativeStudybetweenPenicillinand
Ampicillin. Scholars Journal of Applied MedicalSciences, 1(4), 291–294.
Shashank,K.,&Abhay,K.(2013).ReviewArticleChemistryandBiologicalActivitiesof
Flavonoids: An Overview. TheScientificWorldJ., 4 (2), 32–48.
Shatalin, K., Shatalina, E., Mironov, A.,&Nudler, E. (2011).A UniversalDefenseAgainst
Antibiotics in Bacteria-Supplemental. Science, 334(6058), 986–990.
Singh,R.,Medhi,P.,Manju,S.,&Sikdar,K.(2006).FloralcharactersofMorindacitrifolia
L. inBay Islands.International Journal of Noni Research,1(2), 1-4.
Singh,R.,Shrawan,S.,&Shajeeda,B.(2012).HighPerformanceLiquidChromatography (HPLC)analysisofdifferentpartsofMorindacitrifoliaL. InternationalJournalofNoni Research, 7(1), 55-61.
Sinica,P.,Kakad, L., Pise,S.,&Dhembare, J.(2015).Evaluationofphytochemical, antibacterial, antifungal activitiesofleaf extractsof Morinda citrifoliaL. (Linn),Pelagia ResearchLibrary, 6(4),9–12.
Smith,J. (2001). PeptideSequencingbyEdman Degradation. ELS, 1, 1–3.
Sommer,M.&Dantas,G.(2011).Antibioticsandtheresistantmicrobiome.CurrentOpinion in Microbiology, 14(5),556–63.
Soufi, Y., &Boumediene, S. (2016). MS-Based Bacterial Proteomics: Focus on
Dermatologic MicrobialPathogens.Frontiers inMicrobiology, 7, 1–7.
Spaulding,R.,Salgado-Pab,W.,Kohler,L.,Horswill,R.,Leung,M.,&Schlievert,M. (2013).Staphylococcalandstreptococcalsuperantigenexotoxins.ClinicalMicrobiology Reviews, 26 (3),422–447.
Srivastava,R.,&Shukla,Y.(1996).SomechemicalconstituentsfromCentellaasiatica.
IndianDrugs, 33(5), 233– 234.
Stephen,B.,Hammes-Schiffer,S. (2003).Aperspectiveonenzymecatalysis.Science,
301(5637), 1196-202.
Stevens, D. (2006). Streptococcal and Staphylococcal Infections Tropical Infectious
Diseases. (Second Edition), 356-368.
Sticher, O. (2008). Natural product isolation. Natural Product Reports, 25(3), 517–54. Stuart, H. (2005).Essential Microbiology. UK: John Wiley&SonsLtd., 454.
Su,B.,Pawlus,D.,Jung,H.,Keller,J.,McLaughlin,L.,& Kinghorn,D.(2005).Chemical Constituents of the Fruits of Morinda citrifolia L. (Noni) and Their Antioxidant Activity. J. Nat. Prod., 68 (4), 592-595.
Subban,R.,Veerakumar,A.,Manimaran,R., Hashim,K.,& Balachandran,I.(2008).Two new flavonoids fromCentella Asiatica.Journal of Natural Medicines, 62, (3), 369-373.
Sulaiman,F.,Sajak,B.,Ooi,L.,&Supriatno,S.(2011).Effectofsolventsinextracting polyphenols andantioxidants of selectedraw vegetables. JFood Compos. 24, 506-515.
Suntornsuk,L.,&Anurukvorakun,O.(2005).Precisionimprovementfor theanalysisof flavonoidsinselectedThaiplants by capillary zoneelectrophoresis.Electrophoresis,26 (3), 648–660.
Suraj, N., Mali, P., &Sapkal, M. (2015). Antimicrobial and Antibiotic Resistance.
International Journal of Pharmacyand Pharmaceutical Research, 4 (1), 184-189.
Sylwester,C.(2013).ChromatographyinBioactivityAnalysisofCompounds.In:DeanF.
Martin and Barbara B. MartinColumn Chromatography. Poland:InTech, 99-122.
Taemchuay,D.,&Rukkwamsuk,T.(2009).AntibacterialActivity ofCrudeExtractsof CentellaAsiatica againstStaphylococcusaureusinBovineMastitis.Kasetsart Veterinarians, 19(3), 119–128.
Takashima,J.,Ikeda,Y.,Komiyama,K.,Hayashi,M.,Kishida,A.&Ohsaki,A.(2007).
New constituents from theleaves ofMorinda C., Chem. Pharm. Bull,55 (2), 343-345.
Takashima,J.,Ikeda,Y.,Komiyama,K.,Hayashi,M.,Kishida,A.,&OhsakiA.(2007).
NewConstituentsfromtheLeavesofMorindacitrifolia. ChemPharmBull,55(2),343-
345.
Thamyris,etal.,(2014).Evaluationofantitumorandantimicrobialactivity ofMorinda citrifoliaL.grown in Southeast Brazil. Acta Cir Brasileira,29 (2), 10–14.
Thomas,F.,& Rima,K.(2011).ACDCFrameworkfor PreventingInfectiousDiseases: Sustaining theEssentialsandInnovating fortheFuture.Atlanta,Georgia.CDCID Framework, 1–33.
Tiwari,P.,Kumar,B.,Kaur,M.,Kaur,G.,&Kaur,H.(2011).Phytochemicalscreeningand extraction: a review.International PharmaceuticaSciencia, 1 (1). 98–106.
Tiwatt,K.,Thongphasuk,P.,Chamulitrat,W.,&Wink,M.(2008).Triterpenesaponinsfrom
Chenopodiumquinoa Willd. Phytochemistry, 69,1919-1926.
Toru,I.,Nagai,M.,Taniguchi,A.,Moriyama,H.,& Hoshi,K.(2007).Inhibitoryeffectsof methylbrevifolincarboxylateisolatedfromPhyllanthusniruriL.onplateletaggregation. Biological &Pharmaceutical Bulletin, 30(2), 382–384.
Tuli,L.,&Ressom,H.(2009).LC–MSbaseddetectionofdifferentialproteinexpression.
Journal of Proteomics & Bioinformatics, 2(202),416–438.
Udoh,I.,Asamudo,U.,Bala,N.,& Enwongo,O.(2012).InternationalJournalof PharmaceuticalResearch InhibitoryEffectofVaryingConcentrationsof LeavesExtracts ofCentellaAsiatica(GotuKola)onSomeMicroorganismsofMedicalImportance,3(2),
142–148.
Ullah,O., Sultana,S.,Haque,A.,&Tasmin,S.(2009).Antimicrobial,cytotoxicand antioxidant of Centella Asiatica. Eur. J. Sci.Res., 30, 260-264.
Unno,T.,Sugimoto,A.,&Kakuda,T.(2004).Xanthineoxidaseinhibitors fromtheleaves ofLagerstroemia speciosa(L.) Pers. JEthnopharmacol., 93, 391–395.
Usha,R.,Sangeetha,S.,&Palaniswamy,M.(2010).AntimicrobialActivityofaRarely
Known Species, Morinda citrifoliaL, EthnobotanicalLeaflets, 14 (1), 306-311.
Vadlapudi, V. (2012). Antimicrobial profileof crude extracts Calotropis procera and CentellaAsiaticaagainstsomeimportantpathogens. IndianJournalofScienceand Technology, 5 (8), 3132–3136.
Vander,G.,Christofk,R.,Schuman,E.,Subtelny,O.,Sharfi,H.,Harlow, E.,& Cantley,C. (2010).Identificationofsmallmolecule inhibitorsof pyruvatekinaseM2.Biochemical Pharmacology, 79(8), 1118–1124.
Veenstra,D.(2007).Globalandtargetedquantitativeproteomicsforbiomarkerdiscovery.
JournalofChromatography.B,AnalyticalTechnologiesintheBiomedicalandLife
Sciences, 847 (1), 3–11.
Venter,R.(2014).TheGlobalCrisisofAntibioticResistance.Pharmacologymatters.British pharmacologysociety,(3), 9.
Verma,V.(2014).AreviewonHPLCandRP-HPLCanalysismethod.IndianPharmacology and PharmacyResearch (IPPR), 1 (1), 1-6.
Veronika, M. (2004).Practical High-Performance Liquid Chromatography. 4th ed.
Switzerland:John Wiley&Sons, 159-175.
Vesela,E.,&Robert,P.(2010).ConventionalApproachesforSamplePreparationforLiquid
ChromatographyandTwo-DimensionalGelElectrophoresis.In:HarounN.Shah,Saheer
E.GharbiaMassSpectrometryforMicrobialProteomics.London,UK:JohnWileyand
SonsLtd., 117–142.
Vilhelmsson,O., &Miller,J.(2002). Synthesisof PyruvateDehydrogenasein StaphylococcusaureusIsStimulatedby OsmoticStressTheseinclude:Synthesisof PyruvateDehydrogenaseinStaphylococcusaureusIsStimulatedby OsmoticStress,68 (5), 2353–2358.
Voigt,B.,Schweder,T.,Becher,D.,Ehrenreich,A.,Gottschalk,G.,Feesche,J.,Maurer,H.,
&Hecker,M.(2004).AproteomicviewofcellphysiologyofBacilluslicheniformis. Proteomics,4 (5),1465-90.
Voukeng, K.,Kuete,V.,Dzoyem, P.,Fankam, G.,Noumedem,K., Kuiate,R., &Pages, M. (2012).Antibacterialandantibiotic-potentiationactivitiesofthemethanolextractofsome CameroonianspicesagainstGram-negativemultidrug-resistantphenotypes.BMC research notes, 5, 299.
Vranakis,I.,Goniotakis,I., Psaroulaki, A., Sandalakis, V.,Tselentis, Y.,Gevaert,K.,& Tsiotis,G. (2014). Proteome studiesof bacterialantibiotic resistancemechanisms. Journal of Proteomics, 97, 88–99.
Walgren,L.,& Thompson,C.(2004).Applicationofproteomictechnologiesinthedrug development process. Toxicology Letters, 149(1-3), 377–85.
Walid,E.,&Awad,M.,(2015).HPLCAnalysisofQuercetinandAntimicrobialActivityof
ComparativeMethanol Extracts of Schinus molle L., 4(11), 550–558.
Wang, D., Zetterstrom, E., Gabrielsen, M., Beckham, H., Tree, J.,Macdonald, E.,&Roe,J. (2011).Identificationofbacterialtargetproteinsfor thesalicylideneacyl hydrazideclass of virulence-blocking compounds.The Journal of Biological Chemistry, 286 (34),
29922–31.
Wang,L., Wang,B.,Li,H.,Lu,H., Qiu,F.,Xiong,L.,&Jing,H. (2012). Quercetin,a flavonoidwithanti-inflammatory activity,suppressesthedevelopmentofabdominal aortic aneurysmsin mice. European Journal of Pharmacology, 690(1-3), 133–141.
Wang, M., Wang,S., Sun, Q.,&Wu,L. (1996). Studies on the chemical constituents of the rhizomes ofImperata cylindrica. ChineseJour.of Med. Chem., 6 (3),192-194.
Wang,S.,Duan,J.,&Fang,N.(2004).StructuralfeaturesofapolysaccharidefromCentella Asiatica. ChineseChemicalLetters, 15,(2), 187–190.
Wei,S., Wee,W.,Siong,F.,&Syamsumir,F.(2011).Characterizationofantimicrobial, antioxidant, anticancerpropertiesandchemicalcompositionofSauropus androgynus stem extract. Acta medicaLituanica, 18 (1), 12–16.
Weiss,A.,Delproposto,J.,& Giroux,N.(2004).High-throughputphenotypic profiling of gene-environmentinteractionsby quantitativegrowthcurveanalysisinSaccharomyces cerevisiae.Anal Biochem., 1(1), 23-34.
Wenjie,G.,Wen,H.,Hailiang,L.,Cheng,Q.,Yan,W.,Yang,S.,&Qiang,X.(2012).
Mitochondria-dependentapoptosisofconA-ActivatedTlymphocytesinducedbyAsiatic acid forpreventingmurinefulminant hepatitis. Plos One, 9, 1-10.
WHO(2007).WorldHealthOrganisationguidelinesforassessingquality ofherbal medicines with referenceto contaminants and residues, Geneva:WHO.
Wojnicz,D.,Tichaczek-Goska,D.,& Kicia,M.(2013).EffectofAsiaticandursolicacids ongrowthandvirulencefactorsofuropathogenic Escherichiacoli strains.Turkish Journal of Biology, 37(5), 556–564.
Wong,C.,Hag,M.,&Boey,L.(2012).Chemicalconstituentsandantibacterialactivityof
Melastoma malabathricumL.Nat Prod Res., 26, 609-18.
WorldHealthOrganisation(2014).The10leadingcausesofdeathintheworld,2000and
2012. Retrieved from: http://www.who.int/mediacentre/factsheets/fs310/en/.Last accessed on: 01/02/2016.
Woznicka,E.,Kuzniar,A.,Nowak,D.,Nykiel, E.,Kopacz,M.,Gruszecka, J.,& Golec,K. (2013).Comparativestudy ontheantibacterialactivity ofsomeflavonoidsandtheir sulfonic derivatives. Acta PoloniaePharmaceutica-DrugResearch, 70(3), 567–571.
Yadav,K., Singh,G., Singh, S.,Gautam,B.,& Saad,I.(2012). Potentialtherapeutic drug targetidentificationinCommunity Acquired-MethicillinResistantStaphylococcus aureus (CA-MRSA)usingcomputationalanalysis. Bioinformation, 8(14),664–72.
Yang,Q.,Qiu,H.,Guo,W.,Wang,D., Zhou,X., Xue,D.,&Wang,Y.(2015).Quantitative
1H-NMR method for the determination of Tadalafil in bulk drugs and its tablets. Molecules, 20 (7), 12114–12124.
Yerlekar,A.,&Dudhe,P.(2014).AReviewonStudyandComparisonbetween2DGel
Electrophoresisand Mass Spectrometry.Iosrjournals.org, 16(2), 97–104.
Yun,S.,Choi,C.,Kwon,S.,Park,G.,Cho,K., Kwon,K.,&Kim,I.(2011).Quantitative proteomic analysisofcellwallandplasma membrane fractionsfrommultidrug-resistant Acinetobacter baumannii. Journal of Proteome Research, 10(2), 459–469.
Zahid,L.,& Satyajit,S. (2012).Isolation ofNatural Productsby PreparativeHigh PerformanceLiquidChromatography (Prep-HPLC).In:SatyajitD.SarkerandLutfun NaharNatural ProductsIsolation. 3rdEd. New York: Springer Science, 255-274.
Zhang,X.,Wu,J.,Dou,Y.,Xia, B.,Rong,W.,Rimbach,G.,&Lou,Y.(2012).Asiaticacid protectsprimary neuronsagainstC2-ceramide-inducedapoptosis.EuropeanJournalof Pharmacology, 679(1-3), 51–59.
Zhang,Y.,Follow,R.,Shan,B.,Baek,M.,&Yates,R.(2013).ProteinAnalysisby
Shotgun / Bottom-up Proteomics. Chemical Reviews, 113(4), 2343–2394.
Zhang,Y.,Xu,B.,Kinoshita,N.,Yoshida,Y.,Tasaki,M.,Fujinaka,H.,&Yamamoto,T. (2015).Label-freequantitativeproteomicanalysisrevealsstrong involvementof complementalternativeandterminalpathwaysinhuman glomerular sclerotic lesions. Journal of Proteomics, 123, 89–100.
ZhengJ.,Liu,D.,Zhao,Q.,Su,J.,Yan,P.,Chen,L.,Xiao,Y.,&Zhang,M.(2012).
EnzymaticextractionandantibacterialactivityofaucubinfromEucommiaulmoides
leaves. Journal of Chinesemedicinal materials, 35(2),3
Essay Writing Service Features
Our Experience
No matter how complex your assignment is, we can find the right professional for your specific task. Global Assignment is an essay writing company that hires only the smartest minds to help you with your projects. Our expertise allows us to provide students with high-quality academic writing, editing & proofreading services.Free Features
Free revision policy
$10Free bibliography & reference
$8Free title page
$8Free formatting
$8How Our Essay Writing Service Works
First, you will need to complete an order form. It's not difficult but, in case there is anything you find not to be clear, you may always call us so that we can guide you through it. On the order form, you will need to include some basic information concerning your order: subject, topic, number of pages, etc. We also encourage our clients to upload any relevant information or sources that will help.
Complete the order formOnce we have all the information and instructions that we need, we select the most suitable writer for your assignment. While everything seems to be clear, the writer, who has complete knowledge of the subject, may need clarification from you. It is at that point that you would receive a call or email from us.
Writer’s assignmentAs soon as the writer has finished, it will be delivered both to the website and to your email address so that you will not miss it. If your deadline is close at hand, we will place a call to you to make sure that you receive the paper on time.
Completing the order and download